what is the evidence ? Enhace trial Prowess trial Address trial APACHE score 25 or more means patients is almost died then why to give? (SSC guideline2008) what does all th …

An orthopedic surgeon commented to me today that he (anecdotally) sees more intraoperative bleeding in patients taking serotonergic antidepressants than those not on these antidepr …

A recent trauma case involving major hemorrhage, along with this question on gasexchange, have me wonder whether the promise of a synthetic blood substitute is any closer? I remem …

I've been hearing a bit about rivaroxaban (Xarelto) but haven't come across any patients on it as yet. Does anyone have an idea of what sort of role it will play? Will it replace w …

I have been referred a 51 year old with a somewhat-stable ruptured kidney following a fall from a bicycle four days earlier. Other than some soft tissue bruising, the man suffered …

I recently had a case that made be consider: is there any evidence or formal guidelines for the timing of low-molecular weight heparin (and other anti-coagulants) before and after …

The use of rFVIIa in severe postpartum hemorrhage is still an off-label use and remains controversial. When is the most appropriate time to use rFVIIa and what are the intraoperat …

I'm confused after something that happened today. I was involved in a re-do total hip replacement that had a lot of bleeding. We ended up transfusing 10 units of red cells and then …