sevo,des,iso how they work? where in the brain , brain stem ? RAS? which receptors? gaba ,nmda ? anybody has any idea any evidence to support? where where where?????/

This is a somewhat controversial question that I've heard various answers and opinions on. If I'm going to give a dose of dexamethasone for antiemetic prophylaxis how much should I …

Given that the CVP emperor now provably has no clothes, and there are a multitude of devices measuring continuous cardiac output and various other parameters that might be used to …

I recently anesthetized for a total thyroidectomy with a new surgeon who asked me to check the patient's vocal cords at the end of the case. This is not my usual practice for a thy …

When I last investigated the issue there appeared to be a large body of (non-randomized) evidence correlating allogenic blood transfusion during cardiac surgery with adverse outcom …

We have just added Intralipid (10% lipid emulsion) to our resuscitation trolley at my maternity hospital for use in the resuscitation of local anaesthetic toxicity. We were mainly …

A breast surgeon suggested to me that paravertebral blocks used for breast surgery may reduce the rate of tumor recurrence (or perhaps GA increases tumor recurrence?). I also saw t …

At what blood pressure do you decide to cancel the elective or semi-elective patient with poorly controlled hypertension? It has been my practice to delay surgery for patients wit …

Over the past decade we have seen a huge amount of interest in simulation-centre training for anesthesia, resuscitation and trauma response, among other areas. There are now centre …

Recently, after placing an epidural in a laboring primigravida I found myself in an energetic discussion with the obstetrician after she overheard me reassuring my patient that the …

One of the colorectal surgeons at our institution has become very eager to restrict 'excessive' (or even moderate) intraoperative fluid use during his surgery. He quotes research s …

We all hope that we will not need to, but prepare for it regardless: the emergency surgical airway. In a cannot-intubate-cannot-ventilate scenario, what is the best technique and …

What is the best technique for confirming adequate depth of anesthesia immediately before insertion of a laryngeal mask? I am not referring to confirming the induction of anesthes …

An orthopedic surgeon commented to me today that he (anecdotally) sees more intraoperative bleeding in patients taking serotonergic antidepressants than those not on these antidepr …

I've done the occasional paravertebral block for breast surgery and have found the results to be impressive but I know a lot of people feel that breast surgery is not painful enoug …