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sevo,des,iso how they work?

where in the brain , brain stem ? RAS? which receptors? gaba ,nmda ?

anybody has any idea any evidence to support?

where where where?????/

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3 Answers

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Are you a resident? Pick up Miller.

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if you know and understand the theory/hypothesis after reading miller - nobel prize will be on the way for you . no body knows exactly how these agents works . so dont just simplify things stating miller ,lots of facts are hidden and need reserch.

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..."no body knows exactly how these agents works . so dont just simplify things stating miller ,lots of facts are hidden and need reserch."

Absolutely. No-one really knows for sure. Anyone at the recent metting in Christchurch NZ will tell you that anaesthetic agents work on most forms of life, including the NZ trigger fern (To which one of my colleagues added "I think I've done that guy")

There is some evidence that a final common pathway may involve the beta subunit of the chloride pore of the GABA receptor. I can't quite remember, but it may be a taurine residue, in fact. Presumably it works at any level where the Gaba channels are.

[Which just makes me want to dance around singing "Yo GABA GABA! Yo GABA GABA!!". That's a mummy/mommy joke for you.]

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